Intracytoplasmic sperm injection (ICSI) is indicated for the therapeutic approach of male infertility which is offered in SIMRAN IVF best infertility centerin amritsar, when successful IVF is unlikely due to very low mobile sperm count in the ejaculated sperm, in case of obstruction of the male reproductive tract not amenable to surgical repair, abnormal sperm morphology , frozen sperm and in cases of repeated IVF failures.